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Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation
and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach
and PAE cells
Ripretinib inhibits the growth of ROSAKIT K509I cells with an IC50 of 34 ± 10 nM
DMH-1 effectively inhibits the bone morphogenic protein (BMP) ALK2 receptor (IC50 = 108 nM)
Glyco-Obeticholic acid arb sodium Small-molecule binding of the axinGlyco obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is a farnesoid X receptor (FXR) agonist. Product information CAS Number: 863239 60 5 Molecular Weight: 477. 68 Formula: C28H47NO5 Chemical Name: 2 [(4R) 4 [(1R,3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR) 5 ethyl 4,7 dihydroxy 9a,11a dimethyl hexadecahydro 1H cyclopenta[a]phenanthren 1 yl]pentanamido]acetic acid Smiles:
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